Ranked by shared topics, with one result from each original episode.
“The immune system has strategies for filtering these autoimmune cells out of circulation; however, this filter can malfunction due to age, genetic predisposition, disruption of the gut barrier and gut microbiota, or other environmental exposures.”
“Exercise is a huge driver of how well we age because it induces profound molecular shifts that support immune health and might even protect our telomeres – indicators of aging. Exercise might help forestall certain age-related diseases, such as Parkinson's disease, too.”
“But could aging become reversible in the future? Technologies like interrupted cellular reprogramming, in combination with future advances in the field of epigenetics, offer the promise that scientists may eventually be able to develop the means to reverse aging.”
“Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk.”
“Dietary fiber is a broad term that refers to the non-digestible components of fruits and vegetables. Gut microbes break down certain types of fiber, releasing micronutrients trapped in the fiber matrix and producing beneficial metabolic byproducts, such as short-chain fatty acids.”
“Consuming chocolate and cocoa may carry some risks, however, due to their cadmium content and possible effects on the fetus during pregnancy. In this Aliquot, I describe some of the research on the benefits and risks of consuming cocoa and chocolate, as foods or supplements.”
“Non-steroidal anti-inflammatory drugs, or NSAIDs, are among the most widely used drugs worldwide, available in both prescription and over-the-counter forms, such as aspirin, ibuprofen, naproxen, and others.”
“Sugar substitutes are food products or additives that provide the sweet taste of sugar, without the calories. Evidence suggests that sugar substitutes have surprising effects on human metabolism and these effects vary person-to-person, based on the overall makeup of an individual's gut microbiome.”
“Choline is particularly important during pregnancy and breastfeeding, but some evidence suggests that choline supplementation could carry some risks. In this Aliquot, I talk about the science surrounding choline.”
“The benefits of HIIT include improvements in muscle tissue oxidative capacity, enhanced insulin response, improvements in heart function, and increased lactate – an important source of fuel for the heart, brain, and muscles.”