“It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria. In this Aliquot, I explain why mitochondrial cleanup matters for aging, why urolithin A production varies, and what early human studies suggest about its potential benefits.”
“Because some long-chain PFAS travel through a similar pathway, researchers are now asking whether beta-glucans might also help the body eliminate these persistent "forever chemicals."”
“A more useful approach is to focus on what you can do to reduce its effects. In this Aliquot, Dr. Kelly Starrett explains why standing more is not enough, how to build movement into your workday, and why it matters for long-term mobility.”
“Time-restricted eating, which involves taking in food within a small window of time during the day and fasting for the remainder, can improve certain biomarkers of health – even without weight loss – to improve overall health. In Part I of this two-part segment, Drs.”
“Coordination of meal timing with the circadian rhythm can reduce markers of inflammation and affect aspects of metabolic health, including glucose regulation and insulin sensitivity. Animal studies suggest that overnight fasting induces autophagy.”
“Insulin-like growth factor-1, or IGF-1 for short, is a protein that plays critical roles in major growth pathways in the human body. It influences nearly every tissue in the body, especially developmental growth, skeletal muscle and neurons.”
“Recent discoveries in the field of epigenetics suggest we might be able to slow aging, based on the realization that not everyone ages at the same rate. Evidence suggests that drugs or other medical procedures can slow epigenetic aging, but other factors, such as diet and disease states influence it too.”
“Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, and sweets. Lack of sleep also alters the gut microbiota and impairs immunity, putting us at risk for developing acute illnesses like colds and flu.”
“In the setting of COVID-19, vitamin D deficiency drives poor outcomes. Treating patients with calcifediol, a prescription vitamin D analog, might be more effective at increasing vitamin D to therapeutic levels.”
“Statins can reduce the risk of heart disease by 30 to 40 percent due to their ability to increase LDL receptor activity and reduce blood cholesterol levels. Whether the drugs are overprescribed (or perhaps under-prescribed) is a matter of great debate.”