Search results for reproductive health

“Unfortunately, attempts to demonstrate that rapamycin improves human health and lifespan have yet to materialize. However, abundant data demonstrate the role of mTOR inhibition in aging and disease in mice and other animals. This section will focus on these findings.”

“Elevated phthalate levels during pregnancy are linked to a significant shortening of anogenital distance (AGD) in male infants, a key reproductive health marker. A shorter AGD is associated with birth defects like hypospadias and undescended testicles, both of which increase the risk of infertility and testicular cancer.”

“In an observational cohort of 2,545 couples undergoing IVF, women who consumed at least four drinks per week had lower live-birth odds, as did couples in which both partners consumed at least four drinks per week.”

“These particles serve as carriers for toxic chemicals like BPA and PFAS, which can accumulate in our tissues and organs, raising concerns about their role in hormone disruption, reproductive health issues, and even chronic diseases.”

“In addition, evidence suggests that metformin may prevent cognitive losses, improve mental health status, and reduce the risk of cancer. However, metformin may inhibit exercise-induced health benefits, especially regarding muscle mitochondrial adaptations and muscle hypertrophy.”

“Diet, lifestyle, and environmental exposures can drive epigenetic alterations throughout an individual's lifespan to influence health and disease and can even pass to subsequent generations. DNA methylation and histone modification are the primary biochemical processes that drive epigenetic alterations.”

“In this FoundMyFitness deep-dive clip, Dr. Rhonda Patrick reviews human evidence on BPA, microplastics, and reproductive health. She explains how BPA can interact with endocrine signaling and why fertility studies examine mature oocytes, implantation, testosterone, sperm count, motility, and morphology.”

“Our bodies prioritize putting micronutrients in metabolic pathways needed for survival and reproduction over pathways used in long-term health such as DNA damage repair. In this clip, Bruce provides both an evolutionary and a molecular rationale for his theory.”

“Acute inflammation occurs when the body is exposed to harmful stimuli, such as pathogens, damaged cells, or irritants. Chronic inflammation, however, which occurs with obesity or certain disease states, damages cellular components and contributes to ill health.”

“Regular exercise can help preserve physical and cognitive function with age. Aerobic training supports cardiorespiratory fitness and brain health, while resistance and weight-bearing exercise support strength and bone health.”