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“Imagine a drug that improves sleep, reduces stress, sharpens focus, and boosts mood—without cost or side effects. That "drug" is light. Natural light is more than just illumination; it's a potent regulator of our body's internal clock, driving critical processes like hormone release and sleep-wake cycles.”

“Increased intestinal permeability (also known as "leaky gut") – a condition in which gaps form between the tight junctions that join enterocytes – allows pathogens to leak through the intestinal barrier and pass directly into the bloodstream, promoting inflammation through a specialized mechanism involving detection by toll-like receptors.”

“After taking into account other factors, including age, race/ethnicity, poverty/income, tobacco and alcohol consumption, and physical activity, the authors also found that participants with overweight and obesity were nearly four times more likely to have low serum testosterone compared to lean males, independent of SSB consumption.”

“The “Big Mac effect”, a colloquial term coined by Ronald Krauss, refers to this negative impact, which may become the focus of a full-fledged nutritional research study once funding is available.”

“Our modern lifestyle – characterized by low light exposure during the day and high light exposure during the evening and nighttime hours – has dramatic effects on circadian rhythms and, ultimately, our ability to fall asleep and stay asleep.”

“Our modern lifestyle – characterized by low light exposure during the day and high light exposure during the evening and nighttime hours – has dramatic effects on circadian rhythms and, ultimately, our ability to fall asleep and stay asleep.”

“Dr. Huberman contrasts these with effortful pursuits, but this is a conceptual analogy rather than evidence that screens or color produce drug-equivalent dopamine changes. Large peaks can be followed by reduced drive while signaling recovers.”

“UPFs cause metabolic and cognitive changes in less than a week "...just 5 days of a high-calorie diet made the brains of these healthy, normal weight men structurally and functionally similar to people with obesity, and even after cutting the high-calorie foods out of their diet, these changes persisted for at least one week."”

Dan Pardi: Ph.D. candidate studying sleep neurobiology at Stanford and University of Leiden, co-founder of Dan’s Plan online wellness company.