Related Episodes for Biohacks that may lead to optimal telomere length | Elissa Epel

“In 15 people with severe traumatic brain injury, sodium lactate infusion increased brain lactate, pyruvate, and glucose without raising intracranial pressure, and a randomized study in 60 patients with mild traumatic brain injury reported better cognitive recovery than hypertonic saline.”

“Mouse studies of feeding during infection also found different responses across bacterial and viral models, so a minimally processed dietary pattern, regular exercise, and normal hydration and nutrition during illness provide a more useful foundation than one universal food or fasting rule.”

“In an early randomized workplace study, healthy employees who completed an eight-week mindfulness program showed a greater rise in antibodies after influenza vaccination than a waitlist group.”

“A meta-analysis of 49 studies involving 1,863 adults found that protein supplementation during prolonged resistance training produced additional gains in one-repetition maximum strength, fat-free mass, and muscle size compared with training alone.”

“In eight young men, seven days of 1,000 milligrams of NR per day changed selected muscle NAD metabolites but did not alter substrate use, mitochondrial respiration, or signaling involved in adaptation to one hour of endurance exercise.”

“During sauna use, heart rate, and blood pressure rise, returning to below baseline levels after the session. In this clip, Dr. Rhonda Patrick describes how the physiological effects observed during sauna use are comparable to those that occur during physical exercise.”

“It was associated with improved subjective sleep quality, sleep efficiency, and sleep latency. In practice, separating scrolling, worrying, and other wakeful activities from the bed reduces opportunities to rehearse wakefulness there, while getting up briefly removes the effort to force sleep.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

“A separate 46-year study of 5,107 middle-aged men linked each 1 milliliter per kilogram per minute increase in estimated VO2 max with about 45 additional days of life expectancy. High-intensity intervals are one practical way to improve VO2 max.”

“In a randomized study of healthy adults, four four-minute intervals at 90 to 95 percent of peak heart rate performed three times weekly increased VO2 max by 7.2 percent over eight weeks and outperformed work-matched moderate training.”