Cyclic ketogenic diet improved healthspan and improved memory in mice | Eric Verdin

Parent Episode: Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate, HDAC Inhibitors & NAD+

When researchers fed mice a ketogenic diet, the mice gained weight. To overcome this weight gain, investigators cycled the ketogenic diet on and off, and the mice maintained a stable weight. When on a cyclic ketogenic diet, the researchers observed that mice had an increased median lifespan and improved memory. A separate group of investigators, using a portion-controlled ketogenic diet showed similar results. The mice on the portion-controlled ketogenic diet did even better, suggesting that the cyclic nature may be somewhat stressful for the animals. In this clip, Dr. Eric Verdin explains how a cyclic or the portion-controlled ketogenic diet is linked to improvements in lifespan and memory in mice.

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