NAD+ boosters: NR, NMN, and how they affect sirtuins | David Sinclair

Parent Episode: Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More

Nicotinamide adenine dinucleotide, or NAD+, is a cofactor for multiple physiological processes in the body. NAD+ can be synthesized in the body in the NAD+ salvage pathway, or from two of its precursors, nicotinamide mononucleotide and nicotinamide riboside, often referred to as NAD+ "boosters." Boosting levels of NAD+ has been shown to improve lifespan and healthspan in animal models of premature aging and in humans. In this clip, Dr. David Sinclair describes the NAD+ salvage pathway and how boosting cellular NAD+ levels may be beneficial in slowing aging.

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