“Although alcohol may help us feel calm and ready to sleep, it has surprising effects on REM sleep and maybe our waking behaviors too. In this Aliquot, Dr. Matthew Walker, Tim Ferriss, and I discuss some of the risks and surprising effects of alcohol on human health and behavior.”
“Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk.”
“But what does the science say? In this Aliquot, Dr. Jed Fahey and I discuss the pros and cons of eating meat as well as the confounding factors that may influence the risks associated with meat consumption.”
“Continuous glucose monitors – CGMs, for short – are wearable devices that measure blood glucose levels through a tiny sensor placed under the skin. The CGM communicates with your smartphone and provides nearly real-time information about your blood glucose levels.”
“Sugar substitutes are food products or additives that provide the sweet taste of sugar, without the calories. Evidence suggests that sugar substitutes have surprising effects on human metabolism and these effects vary person-to-person, based on the overall makeup of an individual's gut microbiome.”
“Choline is particularly important during pregnancy and breastfeeding, but some evidence suggests that choline supplementation could carry some risks. In this Aliquot, I talk about the science surrounding choline.”
“Exposure to environmental toxins – in the food we eat, the water we drink, and the air we breathe – is largely unavoidable. But monitoring our exposures and implementing diet and lifestyle strategies can help mitigate the risks associated with toxic exposures. In this Aliquot, Dr. Dale Bredesen, Dr. Michael Snyder, and I discuss ways to deal with our increasingly toxic environment.”
“The benefits of HIIT include improvements in muscle tissue oxidative capacity, enhanced insulin response, improvements in heart function, and increased lactate – an important source of fuel for the heart, brain, and muscles.”
“Late-night eating can have negative effects on our health. But time-restricted eating limits the daytime window during which a person eats to take advantage of the time when metabolism is optimized, improving health and even promoting weight loss.”
“Building muscle mass in one's early years is essential for staving off the age-related loss of muscle mass and may promote longevity. In this Aliquot, Dr. Stuart Phillips discusses the importance of building muscle through resistance training and why starting early is important.”