Related Episodes for Dr. Pierre Capel on the Power of the Mind & the Science of Wim Hof

“In a small trial involving adults with obesity, a ketone monoester improved one processing-speed task and selected brain blood-flow measures, providing an early signal for further research. Temperature can also shape alertness and sleep preparation.”

“Dr. Patrick starts with the Finnish observational evidence: frequent sauna use and sessions longer than 19 minutes were associated with lower cardiovascular mortality in middle-aged men. That evidence informs her routine, but it does not make her temperature, duration, or frequency a universal prescription.”

“Manipulating the core body temperature through hot baths, showers, or saunas – which can have a paradoxical effect on reducing core body temperature – can have dramatic effects on our ability to fall asleep.”

“Dr. Brooks's exact practice of waking 96 minutes before dawn comes from the Vedic concept of Brahma Muhurta rather than a tested clinical protocol. Creatine may provide modest cognitive benefits in some settings, although results in healthy adults are mixed.”

In this clip, Dr. Patrick explains how intense exercise beneficially alters tryptophan and kynurenine metabolism in a way that may benefit depression.

“Removing former drinkers from the non-drinker category reveals a different story: One study observed that the lowest risk for cardiovascular disease (i.e., ischemic heart disease) was right below one standard U.S. drink per week — men and women at this level of consumption had an ~18% lower risk compared to nondrinkers.”

“Vasopressin, a pituitary hormone that acts to promote the retention of water by the kidneys and increase blood pressure, is also a social bonding hormone in males — similar to oxytocin in females. Tim recounts his experiences taking vasopressin in college to boost his short term memory.”

“Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in humans. Some of these effects are mediated by increased glutathione, one of the body's most potent antioxidants, to promote brain health.”

“A key component in these processes is the lactate shuttle – a metabolic pathway that facilitates the movement of lactate between tissues so it can be used as an energy source, effectively recycling it and supporting sustained exercise performance.”

“In Aliquot #131, The Muscle and Bone Benefits of Creatine, creatine expert Dr. Darren Candow and I discussed how creatine supplementation affects muscle quality, physical function, and even skeletal health, particularly in older adults.”