Ranked by shared topics, with one result from each original episode.
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“The SCN, in turn, coordinates the body's peripheral clocks, such as those found in the liver, pancreas, muscles, and fatty tissue, driving rhythms of rest and activity that determine eating-fasting cycles.”
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“Peak plasma flavan-3-ol metabolites after the banana smoothie were 84 percent lower than after the capsule, while the low-PPO berry smoothie produced levels similar to the capsule. PPO is released when plant tissue is cut, bruised, or blended and can react with selected polyphenols before they reach circulation.”
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“Longer endurance aerobic exercise seems to be most effective at producing higher levels of FGF21, coinciding with anecdotes you might have heard from runners who have successfully used exercise in this sort of way. Relevant publications Flippo, Kyle H., et al.”
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“A separate study of 17 recently abstinent heavy cannabis users found poorer sleep efficiency, longer sleep onset, and less slow-wave sleep than in 14 drug-free controls, consistent with withdrawal-related sleep disruption.”
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“A separate cohort of 12,388 adults associated vitamin D exposure with 40 percent lower dementia incidence, and a 12-month randomized trial of 183 older adults with mild cognitive impairment found improvements on several cognitive tests with 800 IU per day.”
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In this clip, Dr. Patrick explains how intense exercise beneficially alters tryptophan and kynurenine metabolism in a way that may benefit depression.
“Adequate, quality sleep is essential for the body's recovery and repair, promoting optimal physical and mental health. Getting a good night's sleep can be challenging, especially in our modern world, but we can take steps to overcome those challenges. In this Aliquot, we present a mashup of our best resources on sleep, featuring insights from Dr. Matthew Walker, Dr. Satchin Panda, and me.”
“A May 2025 Nature paper showed taurine uptake may fuel aggressive myeloid leukemias in laboratory and mouse models, illustrating how nutrients beneficial to healthy tissues may also feed certain cancers.”
“In this Aliquot, Drs. Peter Attia, Stuart Phillips, Morgan Levine, Brad Schoenfeld, Michael Snyder, Valter Longo, Martin Gibala, George Church, as well as Kevin and Darya Rose and myself, share our strategies for finding our fitness.”
“For example, sulforaphane promotes the urinary excretion of benzene and acrolein, toxic compounds present in air pollution. But sulforaphane also demonstrates remarkable antibacterial activity: It reduces populations of Helicobacter pylori, or H.”